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B-HT 920 - CAS# 36085-73-1 Size:Solid 2 mg FdUMP inhibits DNA synthesis and

SKU: 59861940411

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B-HT 920 - CAS# 36085-73-1 Size:Solid 2 mg FdUMP inhibits DNA synthesis andTalipexole, also known as B HT920 and Domnin, is a dopamine agonist that is marketed as a treatment for Parkinson's Disease in Japan by Boehringer Ingelheim; it was introduced in 1996. As of December 2014 it was not approved for marketing in the US nor in Europe. Talipexole is a D2 dopamine receptor agonist and interacts both pre and post synaptic receptors. It also is an 2 adrenergic agonist. The main side effects are drowsiness, dizziness,

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Description

FdUMP inhibits DNA synthesis and cell division by reducing normal thymidine production

Inhibition of CKIepsilon yields a perturbation of oscillator function that forestalls light as a zeitgeber

Inhibition of this enzyme's activity by azoles results in decreased amounts of ergosterol

inhibited cell proliferation (IC50 = 31-125 nM) primarily in a cytostatic manner in cell lines that overexpress EGF-R or c-erbB-2

thereby preventing the binding of the MDM2 protein to the transcriptional activation domain of the tumor suppressor protein p53

B-HT 920 - CAS# 36085-73-1 Size:Solid 2 mg FdUMP inhibits DNA synthesis andTalipexole, also known as B HT920 and Domnin, is a dopamine agonist that is marketed as a treatment for Parkinson's Disease in Japan by Boehringer Ingelheim; it was introduced in 1996. As of December 2014 it was not approved for marketing in the US nor in Europe. Talipexole is a D2 dopamine receptor agonist and interacts both pre and post synaptic receptors. It also is an 2 adrenergic agonist. The main side effects are drowsiness, dizziness,

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