Ebrotidine - CAS# 100981-43-9 ide III small-molecule focal adhesion kinase (FAK)

small-molecule focal adhesion kinase (FAK) inhibitor with potential antiangiogenic and antineoplastic activities

InChi: InChI=1S/C28H26N4O3/c1-28-26(34-3)17(29-2)12-20(35-28)31-18-10-6-4-8-14(18)22-23-16(13-30-27(23)33)21-15-9-5-7-11-19(15)32(28)25(21)24(22)31/h4-11

LV′VFas-transduced T lymphocytes expressing high levels of CD25 (top panel) are eliminated by with 66%±7

Chemical Name: 3-(2-chloroethyl)-2-[(2-chloroethyl)amino]-1

in vivo: Twenty hypertensive patients on chronic hemodialysis were given efonidipine 20-60 mg twice daily and amlodipine 2

Ebrotidine - CAS# 100981-43-9 ide III small-molecule focal adhesion kinase (FAK)Ebrotidine, also known as FI 3542, is an H2 receptor antagonist with gastroprotective activity against ethanol , aspirin or stress induced gastric mucosal damage. The antisecretory properties of ebrotidine are similar to those of ranitidine, and approximately 10 fold greater than those of cimetidine. Ebrotidine has anti Helicobacter pylori activity via inhibition of the urease enzyme and the proteolytic and mucolytic activities of the bacterium.