Tecovirimat - CAS# 869572-92-9 aftor (benzenesulfonate) 1-3H3/t11-

1-3H3/t11-

A significant dose-dependent inhibition of xenograft growth in mice is observed following SR18662 treatment that exceeds the effect of ML264 at equivalent doses

is a functionalized cereblon ligand for PROTAC® research and development

Flt-3 and FGFR3 kinases which have been shown to play important roles in the pathology of several cancers

Overexpressed in a variety of human cancers

Tecovirimat - CAS# 869572-92-9 aftor (benzenesulfonate) 1-3H3/t11-Tecovirimat, also known as SIGA 246 and ST 246, is a core protein cysteine protease inhibitor potentially for treatment of smallpox infection. Tecovirimat is a novel antiviral that inhibits the egress of orthopoxviruses by targeting viral p37 protein orthologs. Tecovirimat has shown efficacy in all small animal and nonhuman primate prophylaxis and therapeutic efficacy models of poxvirus induced disease tested to date. Product information CAS Number: