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AT13148 - CAS# 1056901-62-2 60075 N-hexanoic-Tyr-Ile-(6) aminohexanoic amide

AT13148 - CAS# 1056901-62-2 60075 N-hexanoic-Tyr-Ile-(6) aminohexanoic amide

Name: AT13148 - CAS# 1056901-62-2 60075 N-hexanoic-Tyr-Ile-(6) aminohexanoic amide
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SKU: 70692703836
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AT13148 - CAS# 1056901-62-2 60075 N-hexanoic-Tyr-Ile-(6) aminohexanoic amideAT13148, CAS No. 1056901 62 2, is a novel oral multi AGC kinase inhibitor with potent pharmacodynamic and antitumor activity, which shows a distinct mechanism of action from other AKT inhibitors. AT13148 is currently being developed by Astex Pharmaceuticals. AT131148 was identified utilizing high throughput X ray crystallography and fragment based lead discovery techniques. AT13148 caused substantial blockade of AKT, p70S6K, PKA, ROCK and SGK

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Description

N-hexanoic-Tyr-Ile-(6) aminohexanoic amide

Molecular Weight: 861

such as NODI and NOD2

and somewhat lower than that of flesinoxan (pKi

Smiles: CN1N=CC(Cl)=C1C1C=C(SC=1Cl)C(=O)N[C@H](CN)CC1=CC(F)=CC=C1

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