Halofuginone - CAS# 55837-20-2 065 PubMed PMID: 25644580
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Halofuginone - CAS# 55837-20-2 065 PubMed PMID: 25644580Halofuginone, CAS No. 55837 20 2, also known as RU 19110, is a semisynthetic quinazolinone alkaloid anticoccidial derived from the plant Dichroa febrifuga, with antifibrotic and potential antineoplastic activities. Halofuginone specifically inhibits collagen type I gene expression and matrix metalloproteinase 2 (MMP 2) gene expression, which may result in the suppression of angiogenesis, tumor stromal cell development, and tumor cell growth. These
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