DZ2002 ocysteine (SAH) Tanshinone I reduces the LPS-induced

Tanshinone I reduces the LPS-induced expression of TNF-α

Formula: C17H19FN4O2

is noted to have a higher IC50 value of 70

Administration of GKT137831 throughout the 72-hour period of normoxia or hypoxia exposure attenuates HPASMC proliferation under normoxic conditions at the 20 μM concentration but had no effect on proliferation in normoxic HPAECs

BLT-1 (50 μM

DZ2002 ocysteine (SAH) Tanshinone I reduces the LPS-inducedDZ 2002 is a potent reversible inhibitor of S adenosyl L homocysteine hydrolase (SAHH). DZ2002 ameliorates fibrosis, inflammation, and vasculopathy in experimental systemic sclerosis models. DZ2002 prevents the development of experimental dermal fibrosis by reversing the profibrotic phenotype of various cell types and would be a potential drug for the treatment of systemic sclerosis. Product information CAS Number: 33231 14 0 Molecular Weight: 251. 24