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Obatoclax (GX15-070) Catalog No.:M7923-10 CCRIS 3790

SKU: 76703016521

4.6
USD100.00 USD146.00

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Obatoclax (GX15-070) Catalog No.:M7923-10 CCRIS 3790Obatoclax, also known as GX 015 070, a synthetic small molecule inhibitor of the bcl 2 family of proteins with potential pro apoptotic and antineoplastic activities. Obatoclax binds to members of the Bcl 2 protein family, preventing the binding of these anti apoptotic proteins to the pro apoptotic proteins Bax and Bak and so promoting the activation of the apoptotic pathway in Bcl 2 overexpressing cells. The Bcl 2 family of proteins (bcl 2, bcl xl,

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Description

CCRIS 3790

H596 with IC50 ranging from 29 nM to >20 μM

ClC1C=CC(=CC=1)C(OCCN1CCCCC1)C1C=CC=CC=1

Cardiogenol C either solves in water or DMSO generates a similar effect

OC-144-093

Obatoclax (GX15-070) Catalog No.:M7923-10 CCRIS 3790Obatoclax, also known as GX 015 070, a synthetic small molecule inhibitor of the bcl 2 family of proteins with potential pro apoptotic and antineoplastic activities. Obatoclax binds to members of the Bcl 2 protein family, preventing the binding of these anti apoptotic proteins to the pro apoptotic proteins Bax and Bak and so promoting the activation of the apoptotic pathway in Bcl 2 overexpressing cells. The Bcl 2 family of proteins (bcl 2, bcl xl,

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