AZ3146 WP L6 Smiles: CN(C)CCOC1C=CC(=CC=1)/C(=C(/CCCl)\C1C=CC=CC=1)/C1C=CC=CC=1

Smiles: CN(C)CCOC1C=CC(=CC=1)/C(=C(/CCCl)\C1C=CC=CC=1)/C1C=CC=CC=1

Protopine is a naturally occuring benzylisoquinoline alkaloid found in plants of the family papaveraceae It acts as an analgesic and can inhibit histamine H1 receptors

SR10067 was used at 5-10 µM concentration in vitro and in cellular assays

Chemical Name: 5-{2-[4-(1

There is no specific way to reverse the anticoagulant effect of dabigatran in the event of a major bleeding event

AZ3146 WP L6 Smiles: CN(C)CCOC1C=CC(=CC=1)/C(=C(/CCCl)\C1C=CC=CC=1)/C1C=CC=CC=1AZ3146 is a novel and potent Mps1 inhibitor, which was used to probe the role of Mps1's catalytic activity during mitosis. AZ3146 also inhibits FAK, JNK1, JNK2, KSP and Kit. In in vitro kinase assays, AZ3146 inhibited human Mps1Cat with an IC50 (50% inhibitory concentration) of ~35 nM. AZ3146 also efficiently inhibited autophosphorylation of full length Mps1 immunoprecipitated from human cells. Product information CAS Number: 1124329 14 1 Molecular