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Pomalidomide 4-alkylC7-amine - CAS# 2446474-05-9 Catalog No.:M7204-2 69(7):1649-1661

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Pomalidomide 4-alkylC7-amine - CAS# 2446474-05-9 Catalog No.:M7204-2 69(7):1649-1661Pomalidomide 4 alkylC7 amine, CAS No. 2446474 05 9, Cereblon ligand with alkyl linker and terminal amine for onward chemistry Functionalized cereblon ligand for PROTAC research and development; incorporates an E3 ligase ligand plus an alkylC7 linker with terminal amine ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. Product information CAS Number: 2446474 05 9 Molecular Weight: 422. 91

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Description

69(7):1649-1661

with an IC50 of ∼17 nM

PubMed PMID: 11082439

FH1 was suggested to be supplemented into the culture medium on day 21 at a concentration of 15-20 μM to enhance hepatocyte functions in vitro over period of 9 days

This drug may represent an additional therapeutic paradigm for the treatment of XFG

Pomalidomide 4-alkylC7-amine - CAS# 2446474-05-9 Catalog No.:M7204-2 69(7):1649-1661Pomalidomide 4 alkylC7 amine, CAS No. 2446474 05 9, Cereblon ligand with alkyl linker and terminal amine for onward chemistry Functionalized cereblon ligand for PROTAC research and development; incorporates an E3 ligase ligand plus an alkylC7 linker with terminal amine ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. Product information CAS Number: 2446474 05 9 Molecular Weight: 422. 91

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