R788(prodrug of R406) Size:Solid 2 mg CH-223191 blocked the binding of

CH-223191 blocked the binding of TCDD to AhR and inhibited TCDD-mediated nuclear translocation and DNA binding of AhR

Chemical Name: 4-{7-[6-cyano-5-(trifluoromethyl)pyridin-3-yl]-8-oxo-6-sulfanylidene-5

InChiKey: BIZNHCWFGNKBBZ-JLHYYAGUSA-N

is a nicotinic α3β4 antagonist potentially for the treatment of cocaine abuse

OC(=O)C(O)=O

R788(prodrug of R406) Size:Solid 2 mg CH-223191 blocked the binding ofFostamatinib, also known as R 788 and R 935788, is an orally active, potent and selective Syk kinase inhibitor with potential anti inflammatory and immunomodulating activities. Fostamatinib is also a pro drug of R 406. Fostamatinib inhibits Syk kinase mediated IgG Fc gamma receptor signaling, resulting in inhibition of the activation of mast cells, macrophages, and B cells and related inflammatory responses and tissue damage. Product information CAS