CRISPR Editing Tool Box Catalog No.:LI30010-2S 311 nM and 39 nM

311 nM and 39 nM for PI3Kα

including JMJD isoforms

including the premature-aging disease Hutchinson-Gilford progeria syndrome (HGPS)

17(2):204-12

Chemical Name: 2-allyl-1-(6-(2-hydroxypropan-2-yl)pyridin-2-yl)-6-((4-(4-methylpiperazin-1-yl)phenyl)amino)-1

CRISPR Editing Tool Box Catalog No.:LI30010-2S 311 nM and 39 nMProduct Information A very useful small molecule collection to improve CRISPR editing efficacy, 2 mg solid each for the following compounds: SCR7: a NHEJ inhibitor promotes the efficiency of HDR 45 fold for CRISPR editing in both human and mouse cell lines. RS 1: a RAD51 Stimulatory compound enhances CRISPR Cas9 and TALEN mediated knock in efficiency. (Z) 4 Hydroxytamoxifen: a previously characterised as an Estrogen Receptor antagonist and now found