BRAF inhibitor - CAS# 918505-61-0 10597 both basal and IGF stimulated

both basal and IGF stimulated Akt1 and Akt2 phosphorylation are inhibited in mouse lung

These mediators are critical factors in the inflammatory processes

450839-40-4

03 μM for η-CRD2 (PKCη surrogate peptide)

InChi: InChI=1S/C5H9NO3

BRAF inhibitor - CAS# 918505-61-0 10597 both basal and IGF stimulatedVemurafenib Analog is a potent BRAF inhibitor and the isomer of Vemurafenib. Vemurafenib, also known as PLX4032, RG7204 or RO5185426, is an orally bioavailable, ATP competitive, small molecule inhibitor of BRAF(V600E) kinase with potential antineoplastic activity. Vemurafenib received FDA approval for the treatment of late stage melanoma on August 17, 2011. Product information CAS Number: 918505 61 0 Molecular Weight: 456. 47 Formula: C22H18F2N4O3S