PHA-665752 Catalog No.:M7762-10 9-hexahydro-2H-pyrrolo[3

9-hexahydro-2H-pyrrolo[3

Cloperastine is a drug with a central antitussive effect

Smiles: CC1=CN=C(NS(=O)(=O)C2=CC=CN=C2C2C=CC(=CC=2)C2=NN=CO2)C(=N1)OC

CAS Number: 2154342-56-8

Smiles: NC(=N)SCC1=CC=C(CSC(N)=N)S1

PHA-665752 Catalog No.:M7762-10 9-hexahydro-2H-pyrrolo[3PHA665752 is a potent and selective inhibitor of c Met HGF SF (IC50 values are 9, 68, 200, 1400, 3000, 3800 and 6000 nM for MET, Ron, Flk 1, c abl, FGFR1, EGFR and c src respectively). PHA 665752 suppresses the hepatocyte growth factor induced cell proliferation and radioresistance in nasopharyngeal carcinoma cells. PHA 665752 reverses lung premalignancy induced by mutant K ras. PHA 665752 induced apoptosis of a lung adenocarcinoma cell line derived