Olprinone Hydrochloride dium Channel inhibitor 1 BIBW2992 is currently undergoing Phase

BIBW2992 is currently undergoing Phase III clinical trials for non-small cell lung carcinoma (NSCLC) and breast cancer

InChiKey: QMGHHBHPDDAGGO-IIWOMYBWSA-N

Chemical Name: 1-ethyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1

Ergosterol is a sterol found in fungi

It inhibits phosphorylation of the mTORC1 substrates 4E-BP1 and S6K1 as well as the mTORC2 substrate AKT in diverse cancer models in vitro and in vivo

Olprinone Hydrochloride dium Channel inhibitor 1 BIBW2992 is currently undergoing PhaseOlprinone (INN) is a cardiotonic agent and a specific phosphodiesterase (PDE) III inhibitor. It has been marketed in Japan since 1996. Olprinone attenuates excessive shear stress through up regulation of endothelial nitric oxide synthase in a rat excessive hepatectomy model. Olprinone reduces the development of multiple organ dysfunction syndrome in mice. Product information CAS Number: 119615 63 3 Molecular Weight: 286. 72 Formula: C14H11ClN4O