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4SC-202 - HDAC/LSD1 Dual Inhibitor. CAS# 1186222-89-8 size:2 mg solid DASA-58 (ML203)

4SC-202 - HDAC/LSD1 Dual Inhibitor. CAS# 1186222-89-8 size:2 mg solid DASA-58 (ML203)

Name: 4SC-202 - HDAC/LSD1 Dual Inhibitor. CAS# 1186222-89-8 size:2 mg solid DASA-58 (ML203)
Brand: armz-ageddon.com
SKU: 97405667530
Price: 55.00 USD
Availability: InStock
Rating: 4.2826 (27 reviews)

SKU: 97405667530

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4SC-202 - HDAC/LSD1 Dual Inhibitor. CAS# 1186222-89-8 size:2 mg solid DASA-58 (ML203)4SC 202, CAS No. 1186222 89 8, is a potent, selective and orally bioavailable HDAC LSD1 dual Inhibitor. It inhibits class I HDAC with IC50 of 1. 20M, 1. 12 M, and 0. 57M for HDAC1, HDAC2, and HDAC3, respectively. It also displays inhibitory activity against Lysine specific demethylase 1 (LSD1). 4SC 202 has very high selectivity over ClassIIa IIb III HDACs. In HeLa cells, it induces hyperacetylation of histone H3 with EC50 of 1. 1 M. It induces a G2 M

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Description

DASA-58 (ML203)

as evidenced by a 23% reduction in epidermal thickness

UNC0379 was used at 10-30 µM in vitro assays

and improves glycaemic control

Smiles: NC(=O)C1=CC(=CC=C1)C1=CC(NC2C=CC(=CC=2)OC(F)(F)F)=NC=N1

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