OSI-906 Size:10mg solid A significant increase of the

A significant increase of the animal lifespan in the test groups (from 4

Chemical Name: 4-[1-Cyclohexyl-4-(4-fluorophenyl)-1H-imidazol-5-yl]-2-pyrimidinamine dihydrochloride

ClH/c18-6-8-26-9-7-19-11-3-1-2-10-14(11)17(25)21(16(10)24)12-4-5-13(22)20-15(12)23

PRI-724 treatment reduces the fibrosis induced by CCl4 or BDL

AEE788 inhibits the growth of Daoy

OSI-906 Size:10mg solid A significant increase of theOSI 906, is a n orally bioavailable small molecule inhibitor of the insulin like growth factor 1 receptor (IGF 1R) with potential antineoplastic activity. OSI 906 selectively inhibits IGF 1R, which may result in the inhibition of tumor cell proliferation and the induction of tumor cell apoptosis. Overexpressed in a variety of human cancers, IGFR 1 stimulates cell proliferation, enables oncogenic transformation, and suppresses apoptosis. Product