Derazantinib - CAS# 1234356-69-4 6049 thiophenecarboxamide IKK-2 inhibitors

thiophenecarboxamide IKK-2 inhibitors

Molecular Weight: 353

calcium/calmodulin-dependent protein kinase 1 and smooth muscle myosin light-chain kinase

InChi: InChI=1S/C9H2Cl4O2/c10-6-4-2(14)1-3(15)5(4)7(11)9(13)8(6)12/h1H2

Chemical Name: 2-((5-bromo-2-((3

Derazantinib - CAS# 1234356-69-4 6049 thiophenecarboxamide IKK-2 inhibitorsDerazantinib, CAS No. 1234356 69 4, also known as ARQ 087, is an orally bioavailable inhibitor of the fibroblast growth factor receptor (FGFR) with potential antineoplastic activity. FGFR inhibitor ARQ 087 binds to and potently inhibits the activity of FGFR subtypes 1, 2 and 3. This may result in the inhibition of FGFR mediated signal transduction pathways, tumor cell proliferation, tumor angiogenesis and tumor cell death in FGFR overexpressing tumor