Phospho-Bcl-2 (T74) Polyclonal Antibody, 50ul DNA Fragments The C1 domain does not

The C1 domain does not bind the diacylglycerol (DAG)

The phospholipase D family member 3 is a single-pass type II membrane protein and contains two PLD phosphodiesterase domains

The encoded protein may be involved in development of the placenta

Y527 is this tyrosine

Its chromosomal location has linked it to a specific translocation event identified in patients with acute promyelocytic leukemia but it is also involved in normal hematopoiesis as well as growth factor and cytokine receptor signaling

Phospho-Bcl-2 (T74) Polyclonal Antibody, 50ul DNA Fragments The C1 domain does notBCL2 (BCL2, apoptosis regulator) encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Alternative splicing results in multiple transcript variants.