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Hydrogen sulfide guards myoblasts from ferroptosis by inhibiting ALOX12 acetylation

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Verify the report on the official SGS website with ID " QIP-ASR231082 "

Kouichi Tamura has received honoraria/lecture fee from AstraZeneca, Novartes, Bayer, Otsuka Pharmaceutical, Boehringer Ingelheim, Fuji Pharma, Kyowa Kirin, Ono Pharmaceutical, Sanwa Kagaku, Mochida Pharmaceutical, Kowa, Eli Lilly, Novo Nordisk, commissioned clinical trials, contract research and joint research funding: AstraZeneca, Bayer, Novartis, Chinook, Otsuka Medical Devices, Novo Nordisk, Terumo, Variatris, and Kowa, and, Scholarship donations: Otsuka Pharmaceutical, Bayer, Mochida Pharmaceutical, and Boehringer Ingelheim

Through multi-omics profiling combined with cellular and animal model validation, we provide evidence that GCLC is not merely a biomarker but a mechanistic contributor to disease pathogenesis