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Mullins et al

Naming the blood glucose-lowering substance 'pancreine'

Planning can help: Don't skip meals earlier in the day to "save calories" for an event, as this can lead to overeating despite the medication

doi: 10.1016/j.bbrc.2018.12.149 56 LiZLiSWangNXuePLiY

In a prospective real-world cohort of 194 adults with type 2 diabetes initiating semaglutide or dulaglutide, only 49% achieved 5% weight loss by 12 months meaning that just under half of treated patients did not meet the threshold conventionally defined as clinically meaningful (Vozza et al., 2025)

A warehouse worker in Michigan with severe obesity and mounting health complications may have no path to affordable GLP-1 therapy, while a tech worker in Silicon Valley receives the same medication with a $25 copay through an employer plan that absorbs the cost without blinking