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Published online May 23, 2025

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PMID: 28698222

Key Scientific Applications GLP-1S is a long-acting GLP-1 receptor agonist designed to mimic endogenous glucagon-like peptide-1 signaling

These medicines work by mimicking the action of naturally occurring GLP-1, an incretin hormone released by the intestine in response to food intake

Women taking popular medicines for weight loss and diabetes, sometimes referred to as skinny jabs, are being reminded to use effective contraception while taking these medicines and, in some cases, for up to two months between stopping the medicine and trying to get pregnant, warns the U.K.s Medicines and Healthcare products Regulatory Agency (MHRA)akin to the U.S