Ob-R Polyclonal Antibody, 20ul[BT-AP06324] Cryopreservation Diseases associated with ELOVL2 include

Diseases associated with ELOVL2 include gastric antral vascular ectasia and malignant melanoma

The ELOVL proteins act as catalysts in fatty acid elongation reduction and localize to the endoplasmic reticulum (ER)

Chromosomal rearrangements and altered expression of this gene have been implicated in tumor metastasis

thought to form the base of the dynein arm

Suppresses Src-dependent tyrosine phosphorylation and activation of PDPK1 and its downstream signaling

Ob-R Polyclonal Antibody, 20ul[BT-AP06324] Cryopreservation Diseases associated with ELOVL2 includeThe protein encoded by LEPR belongs to the gp130 family of cytokine receptors that are known to stimulate gene transcription via activation of cytosolic STAT proteins. This protein is a receptor for leptin (an adipocyte specific hormone that regulates body weight), and is involved in the regulation of fat metabolism, as well as in a novel hematopoietic pathway that is required for normal lymphopoiesis. Mutations in this gene have been associated with