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The SELECT trial showed meaningful reductions in major cardiovascular events in patients with established cardiovascular disease who used semaglutide for weight management

is a co-founder and has financial interest in Stemloop, Inc., Pearl Bio, Gauntlet Bio, and Synolo Therapeutics

Within the gastrointestinal system, it slows gastric emptying, which prolongs satiety and reduces hunger signals

When participants who had been taking semaglutide were randomized to either continue the medication or switch to placebo after 20 weeks, those who continued treatment maintained their weight loss, while those switched to placebo regained significant weight

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These medications have direct organ protective effects. However, he said more work is now needed to implement the results of the study into clinical practice and improve access to GLP-1 receptor agonists to people who will benefit from them