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FEBS Lett 529:93101 Taylor JM, Ali U, Iannello RC, Hertzog P, Crack PJ (2005) Diminished Akt phosphorylation in neurons lacking glutathione peroxidase-1 (Gpx1) leads to increased susceptibility to oxidative stress-induced cell death

ESA does not alter GPX4 activity but is incorporated into cellular lipids and promotes lipid peroxidation and cell death in diverse cancer cell types

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1.3.3 SETDB1 Among all these H3K9 HMTs, SETDB1 is the only one that catalyzes all three forms of methylation (mono-, di-, and tri-) in vivo and forms various repressive protein complexes both at euchromatic and heterochromatic regions (Padeken et al., 2022)

Analysis of the intrinsically disordered N-terminal fragment of human glucocorticoid receptor fragments revealed that it is characterized by the max of 340 nm, suggesting an external location of Trp residues, whereas trimethylamine N-oxide-induced folding of this fragment resulted in a blue shift of fluorescence maximum by more than 10 nm (Baskakov et al., 1999)

It was done to compare the results with and without the addition of TFA